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Talk:Serotonin–norepinephrine reuptake inhibitor

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SERATONIN or SELECTIVE?

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...er- although I have not graduated yet and am far from an expert I am well aware of selective norepinephrine re-uptake inhibitor (SNRI) antidepressants, but have never heard of the same abbreviation referring to "Serotonin-norepinephrine re-uptake inhibitor" type antidepressant drugs. I believe this may be a misunderstanding on the part of the author and hope a kind professional/academic might find the time to either authenticate, edit, merge or delete this article accordingly.

SNRI is a valid acronym but if one wants an all-inclusive acronym, go with SSNDRI . It should be used along with a needed discussion of dopaminergic re-uptake inhibitors (SDRIs). Buccleugh (talk) 19:42, 20 June 2013 (UTC) buccleugh Thanks all, and all hail the free encyclopedia![reply]

Toby84.43.122.165 (talk) 23:26, 13 January 2008 (UTC)[reply]

OK sorry - think I'm going nuts myself! Have been up far too long writing an unrelated paper & was trying to procrastinate.... Perhaps they are seratonin-norepinephrine RIs...

So long, T 84.43.122.165 (talk) 23:33, 13 January 2008 (UTC)[reply]

SNRI is serotonin norepinephrine reuptake inhibitors, and the "specific" is assumed, probably because SSNRI seemed too long. "Specific norepinephrine reuptake inhibitors" is abbreviated "NRI" with the specific assumed again. Psydzl (talk) 18:18, 11 February 2008 (UTC)[reply]

Ok I was asked to propose this here on the talk page. I have extensive experience w/ these agents and have spent a considerable amount of my adult years studying and marketing these types of medicines. The correct term to describe a dual acting agent (serontonin/norepinephrine) is referred to as an SSNRI which stands for Selective Serotonin Norepinephrine Reuptake Inhibitor. Now not all SNRI's are considered SSNRI's... which may be part of the confusion. Really the first of the class of SSNRI's was duloxetine, a.k.a. Cymbalta. Even Effexor XR can be considered an SSNRI but those are really the only two that act equally on both receptor sites.

So I propose for the sake of accuracy that we correctly refer to this new class as SSNRI rather than lumping them all into the SNRI classification.

In addition if you do a google search on just the term 'SSNRI' the first result is a wikipedia page with the URL en.wikipedia.org/wiki/SSNRI and a title that says, "SSNRI." So it is in fact misleading to then bring the visitor to a page that uses the term SNRI because that is not what they were looking for.

Thoughts? —Preceding unsigned comment added by Mdphd (talk • contribs) 22:04, 21 May 2008 (UTC)[reply]

Mdphd (talk) 22:06, 21 May 2008 (UTC)[reply]

Per MEDMOS, I'm not certain if that change would be appropriate. A PubMed search for "SSNRI" yields only 4 results, and only 2 of these are in English. (This is compared to 2546 for "SSRI" and 184 for "SNRI".) --Arcadian (talk) 02:46, 22 May 2008 (UTC)[reply]

OK, I'm not a clinician, but I teach pharmacology to allied health professionals... and the way I have been teaching it from the textbooks is that SNRI are serotonin noradrenaline reuptake inhibitors, and NARI or NRI are noradrenaline reuptake inhibitors. I think that's standard terminology today, although certainly none of these classes existed at all back when I took pharmacology.

As a medical student currently studying psychiatry I would say that the accepted abbreviation (in the UK at least) is SNRI. If there is confusion the page should be updated to reflect this. Another point id like to raise is the usage of SNRIs, whilst they seem to be popular in America they aren't prescribed much in the UK, at least from my (very limited) experience. 69.137.60.87 (talk) 22:39, 20 April 2011 (UTC)[reply]

I think it would be good to combine both under the shorter title. My choice would be SNRI. With tramadol, however, two less-elegant acronyms, SRI and NRI, are needed (imho, of course) to prevent confusion. buccleugh (talk) 18:36, 20 June 2013 (UTC) buccleugh 68.113.85.127 (talk) 18:31, 20 June 2013 (UTC) buccleugh 68.113.85.127 (talk) 18:29, 20 June 2013 (UTC) 18:23, 20 June 2013 (UTC)68.113.85.127 (talk) —[reply]

Wiki Education assignment: Psychology Capstone

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 26 August 2024 and 6 December 2024. Further details are available on the course page. Student editor(s): SFronduti (article contribs). Peer reviewers: Makylam18, Carolinedean31, Sarah3102, Anlntph, Matthewpalmer03.

— Assignment last updated by Aronov13 (talk) 03:30, 6 October 2024 (UTC)[reply]

Adding information to 'special populations' section providing more in-depth detail for each category and further citations. SFronduti (talk) 02:20, 20 October 2024 (UTC)[reply]

Removed "migraine prevention" from Intro. Latest research from 2018 shows that data does not show sufficient effectiveness in prevention. See C. Sialakis, P. Antoniou. The effect of the selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors in prevention of the tension type headache and migraine: overview of Cochrane and non-Cochrane reviews. Scientific Chronicles 2018; 23(3): 288-302 eoi: http://eoi.citefactor.org/10.11212/exronika/2018.3.4 SFronduti (talk) 05:10, 10 November 2024 (UTC)[reply]

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